The focus of my laboratory research is the neuroendocrine control of ingestive behavior, in particular, the physiological mechanisms by which eating elicits drinking behavior. I also have written two books and a recent review paper regarding benefits and risks associated with the use of psychiatric medications.
Many of the students working in my laboratory learn various surgical procedures including manipulations of the gastrointestinal tract and stereotaxic surgery to implant a cannula into the brain of a rat. Students conduct experiments in which drugs are used to manipulate neurochemical mechanisms to study their involvement in eating and drinking or other behaviors.
More than twenty-five Colgate undergraduates have become co-authors of published journal articles reporting the results of experiments conducted at Colgate.
The Unwell Brain: Understanding the Psychobiology of Mental Health (WW Norton, 2009), developed from my teaching courses in brain and behavior and psychopharmacology.
My more recent book is Psychopharmacology Problem Solving: Principles and Practices to Get it Right (WW Norton, 2014).
Colgate launched in 2015 my digital online course on the edX platform, a MOOC entitled Medicating for Mental Health: Judicious Use of Psychiatric Drugs.
My review entitled "Evidence-Based Pharmacotherapy" appears in the 2019 APA Handbook of Psychopharmacology."
I am fortunate to be a first-generation college graduate who is happy to talk to Colgate students about the advantages and challenges of being a "1st gen." When not working, I play the drums in the alternative/pop band dangerboy. You should hire us!
- BA University of Notre Dame 1970
- MA, PhD Johns Hopkins University 1972, 1974
- Behavioral neuroscience
- Experimental psychology
- Neuroendocrine control of drinking and eating
- Strategies and methods of research in behavioral neuroscience
- Scientific writing
Kraly, F.S. Psychopharmacology Problem Solving: Principles and Practices to Get it Right. WW Norton & Co., Inc., New York, 2014.
Kraly, F.S. Brain Science and Psychological Disorders: Therapy, Psychotropic Drugs, and the Brain. WW Norton & Co., Inc., New York, 2006. (Reissued in 2009 as The Unwell Brain: Understanding the Psychobiology of Mental Health.)
Selected Articles in Professional Journals:
(NOTE: bold text indicates Colgate undergraduate)
Kraly, F.S. Evidence-based Pharmacotherapy. APA Handbook of Psychopharmacology, 2019, 109-135.
Kraly, F.S. Eating provides important physiological signals for satiety and drinking. Physiology and Behavior,2004, 82, 49-52.
Kraly, F.S. & Jones, K.M. Histaminergic activation of endogenous angiotensin II fails to inhibit alcohol intake in rats. Alcohol, 1999, 17, 57-61.
Kraly, F.S., Tribuzio, R.A., Keefe, M.E., Kim, Y.M. & Lowrance, R. Endogenous histamine contributes to drinking initiated without postprandial challenges to fluid homeostasis in rats. Physiology and Behavior, 1996, 58, 1137-1143.
Kraly, F.S., Tribuzio. R.A., Kim, Y.-M., Keefe, M.E., Braun, C.J. & Newman, B.H. Angiotensin AT1 and AT2 receptors contribute to drinking elicited by eating in rats. Physiology and Behavior, 1995, 58, 1099-1109.
Kraly, F.S., Kim, Y.-M., Dunham, L.M. & Tribuzio, R.A. Drinking after intragastric NaCl without increase in systemic plasma osmolality in rats. American Journal of Physiology: Regulatory,Integrative and Comparative Physiology, 1995, 269, R1085-R1092.
Kraly, F.S. & Klinko, C.J. Separate controls for conditioned cephalic phases of acid secretion and drinking in the rat. Physiology and Behavior, 1991, 49, 7-11.
Kraly, F.S. Drinking elicited by eating. In: Progress in Psychobiology and Physiological Psychology, Vol. 14. A.N. Epstein & A. Morrison (Eds.), Academic Press, New York, 1990, 67-133.
Kraly, F.S., Coogan, L.A., Specht, S.M., Trattner, M.S., Zayfert, C., Cohen, A. & Goldstein, J.A. Disordered drinking in developing spontaneously hypertensive rats. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 1985, 248, R464-R470.
Kraly, F.S. Physiology of drinking elicited by eating. Psychological Review, 1984, 91, 478-490.
Kraly, F.S. Preabsorptive pregastric vagally-mediated histaminergic component of drinking elicited by eating in the rat. Behavioral Neuroscience, 1984, 98, 349-355.
Kraly, F.S. Histamine plays a part in induction of drinking by food intake. Nature, 1983, 302, 65-66.
Kraly, F.S. A diurnal variation in the satiating potency of cholecystokinin in the rat. Appetite, 1981, 2, 177-191.
Kraly, F.S., Gibbs, J. & Smith, G.P. Disordered drinking after abdominal vagotomy in rats. Nature, 1975, 258, 226-228.
- Postdoctoral Fellow in Psychiatry, Cornell University Medical College 1974-78
- Director of Colgate study groups to Cardiff, Wales and Wollongong, Australia.
- Content creator of online digital course Medicating for Mental Health on the edX platform.
- National Institutes of Health Research Grants, principle investigator.
- Colgate Alumni Corporation Distinguished Teaching Award (2005).
- Director, Division of Natural Sciences and Mathematics (2008-2011) at Colgate.